平滑肌細胞是多數重要動脈疾病的靶細胞。血管SMC的生長潛力是原發血管病發展中至關重要的異常因素。*新研究表明SMC表達的鈣通道，其表面表達的ICAM-1和VCAM-1，均參與了血管壁的炎癥反應，并與血管疾病的進展和穩定有關。慢性肺組織缺氧能造成血管重塑，肺動脈平滑肌增生，*終導致肺動脈高壓。人血管平滑肌的體外培養可作為血管研究模型，為血管疾病的治療和藥理學研究提供信息，發揮重要作用。
人肺動脈平滑肌細胞提取于人肺動脈組織，二代凍存。每管含有細胞數>5×10^5 cells/ml，此細胞通過對alpha-SMA和Desmin免疫熒光染色驗證，經測試不含有HIV-1、HBV、HCV、支原體、細菌、酵母和真菌。細胞可以達到15倍增。
推薦培養基：平滑肌細胞培養基 (SMCM, Cat. #1101)
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貨號
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3110
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產地
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美國
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縮寫
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HPASMC
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規格
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5 x 10^5 /1ml
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用途
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科研
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儲存
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液氮
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運輸
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干冰
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關鍵字
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人肺動脈平滑肌細胞 HPASMC 人肺動脈平滑肌細胞 HPASMC 人肺動脈平滑肌細胞 HPASMC 人肺動脈平滑肌細胞 HPASMC 人肺動脈平滑肌細胞 HPASMC 人肺動脈平滑肌細胞 HPASMC 人肺動脈平滑肌細胞 HPASMC 人肺動脈平滑肌細胞 HPASMC
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公司簡介
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合肥星肽生物科技有限公司作為專業的ScienCell中國代理商，專業經營實驗室科研用原代細胞、原代細胞專用培養基、原代細胞無血清培養基、干細胞、干細胞培養基、干細胞無血清培養基的研究和開發。合肥星肽生物科技有限公司始終致力于為客戶提供可靠的研究材料以及方便快捷的服務，對購買項目的前期資料提供,中期合同保證,后期貨物跟蹤到*終售后的確保項目準確到位，都有相關專業人士進行維護,確保您在合肥合肥星肽生物科技有限公司公司獲得*上等服務！
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聯系方式
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何經理，合肥星肽生物科技有限公司，Tel：0551-63802898 400-8702-898，
E-mail：[email protected] http://m.cnqiepian.com QQ:514713116
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1.) Wang HL, Peng LP, Chen WJ, Tang SH, Sun BZ, Wang CL, Huang R, Xu ZJ, Lei WF. (2014) 'HMGB1 enhances smooth muscle cell proliferation and migration in pulmonary artery remodeling.'
2.) Ibrahim YF, Wong CM, Pavlickova L, Liu L, Trasar L, Bansal G, Suzuki YJ. (2014) 'Mechanism of the Susceptibility of Remodeled Pulmonary Vessels to Drug?Induced Cell Killing.'
3.) Wang G, Liu X, Meng L, Liu S, Wang L, Li J, Cui C, Meng J, Hu S, Wei Y. (2014) 'Up-Regulated Lipocalin-2 in Pulmonary Hypertension Involving in Pulmonary Artery SMC Resistance to Apoptosis.'
4.) Ibrahim YF, Wong CM, Pavlickova L, Liu L, Trasar L, Bansal G, Suzuki YJ. (2014) "Mechanism of the Susceptibility of Remodeled Pulmonary Vessels to Drug?Induced Cell Killing." J Am Heart Assoc. 3: e000520.
5.) Wang G, Liu X, Meng L, Liu S, Wang L, Li J, Cui C, Meng J, Hu S, Wei Y. (2014) "Up-Regulated Lipocalin-2 in Pulmonary Hypertension Involving in Pulmonary Artery SMC Resistance to Apoptosis." Int j biol sci. 10: 798-806.
6.) Wang HL, Peng LP, Chen WJ, Tang SH, Sun BZ, Wang CL, Huang R, Xu ZJ, Lei WF. (2014) "HMGB1 enhances smooth muscle cell proliferation and migration in pulmonary artery remodeling." Int j clinexppathol. 7: 3836-44.
7.) Zha WJ, Qian Y, Shen Y, Du Q, Chen FF, Wu ZZ, Li X, Huang M. (2013) "Galangin Abrogates Ovalbumin-Induced Airway Inflammation via Negative Regulation of NF-?B."Evid Based Complement Alternat Med. 2013:767689.
8.) Wang G, Zhang Z, Xu Z, Yin H, Bai L, Ma Z, Decoster MA, Qian G, Wu G. (2010) "Activation of the sonic hedgehog signaling controls human pulmonary arterial smooth muscle cell proliferation in response to hypoxia." Biochim Biophys Acta. 1803: 1359-67.
9.) de Frutos S, Nitta CH, Caldwell E, Friedman J, Gonz?lez Bosc LV. (2009) "Regulation of soluble guanylyl cyclase-alpha1 expression in chronic hypoxia-induced pulmonary hypertension: role of NFATc3 and HuR." Am J Physiol Lung Cell Mol Physiol. 297: L475-86.
10.) de Jesus Perez VA, Alastalo TP, Wu JC, Axelrod JD, Cooke JP, Amieva M, Rabinovitch M. (2009) "Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways." J Cell Biol.184: 83-99.
11.) Wang Z, Yuan Z, Jin L. (2008) "Gene delivery into hepatocytes with the preS/liposome/DNA system." Biotechnol J. 3: 1286-95.
12.) Armbruster BN, Li X, Pausch MH, Herlitze S, Roth BL. (2007) "Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand." Proc Natl Acad Sci USA. 104: 5163-8.
